Acyl bromides
Medchemexpress LLC Aclidinium Bromide | 320345-99-1 | 98.96% | C26H30BrNO4S2 | 1 ML
Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist with potential for research into chronic obstructive pulmonary disease (COPD). It has shown potent antagonism of human muscarinic receptors preclinically, with a long residence time at M3 receptors, suggesting potential for sustained bronchodilation. Early clinical studies have indicated low systemic bioavailability and a favorable safety profile.
- Long-acting muscarinic antagonist
- Potential for chronic obstructive pulmonary disease (COPD) research
- Exhibits potent antagonism of human muscarinic receptors
- Long residence time at M3 receptors for sustained bronchodilation
- Low systemic bioavailability
- Favorable safety profile
- Rapidly hydrolyzed in human plasma
TARGETMOL CHEMICALS INC Tarloxotinib bromide 1MG
Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Tarloxotinib bromide (TH-4000) is an irreversible inhibitor of EGFR/HER2. Purity 97.15%
Cayman Chemical p-Benzoyl-L-phenylalnIn 1g
A photoreactive derivative of L-phenylalanine; can be incorporated into synthetic peptides and used as a photolabel to identify the residues involved in peptide-protein interactions; has been incorporated into GPCRs to identify potential ligand binding sites
Medchemexpress LLC Rapacuronium bromide | 156137-99-4 | MFCD00870871 | 98.0% | 677.80 g·mol⁻¹ | C37H61BrN2O4 | 10 MG
Rapacuronium bromide is a non-depolarizing aminosteroid neuromuscular blocker and an allosteric modulator of muscarinic acetylcholine receptors supplied for research use only. It is offered in solid and solution formats across multiple pack sizes and is provided at high purity.
- Non-depolarizing neuromuscular blocker and allosteric modulator of muscarinic acetylcholine receptors.
- Intended for research use only; not for human or veterinary use.
- Available in solid and DMSO solution formats for flexible experimental use.
- High purity (98.0%) suitable for analytical and preclinical studies.
- Provided with CAS number and chemical formula for traceability.
Medchemexpress LLC N6-Benzoyl-9-β-D-arabinofuranosyladenine | 79896-97-2 | 98.2% | C17H17N5O5 | 25 MG
N6-Benzoyl-9-β-D-arabinofuranosyladenine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has shown potential in inhibiting cancer progression. It serves as a valuable tool for research in cardiovascular and oncology fields, enabling exploration of adenosine signaling pathways.
- Adenosine analog
- Primarily targets adenosine receptors
- Exhibits smooth muscle vasodilatory effects
- Demonstrates potential in inhibiting cancer progression
- Valuable tool for cardiovascular research
- Valuable tool for oncology research
- Enables exploration of therapeutic implications of adenosine signaling pathways
Medchemexpress LLC Otilonium bromide | 26095-59-0 | MFCD00079361 | 99.7% | 50 MG
Otilonium bromide (OB) is an orally active mAChR inhibitor and smooth muscle relaxant. It can interfere with the mobilization of calcium in intestinal smooth muscle and is used for research of irritable bowel syndrome.
- Orally active mAChR inhibitor
- Smooth muscle relaxant
- Interferes with calcium mobilization in intestinal smooth muscle
- Used for research of irritable bowel syndrome
AdipoGen Dimidium bromide
Chemical. CAS 518-67-2. Formula C20H18BrN3. MW 380.28. Synthetic. Intercalating probe for nucleic acids. Other applications include the determination of cationic surfactants.
Medchemexpress LLC Benzoyl coenzyme A trilithium | 102185-37-5 | MFCD00078942 | 94.0% | 889.44 g·mol⁻¹ | C28H37Li3N7O17P3S | 5 MG
Benzoyl coenzyme A trilithium is the trilithium salt of benzoyl coenzyme A supplied for research use as an intermediate in CoA-dependent metabolic pathways (CAS 102185-37-5). It is provided as a white to off-white solid with specified storage and solvent stability for biochemical studies.
- White to off-white solid for biochemical research.
- Molecular weight 889.44 g·mol⁻¹.
- Purity 94.0%.
- Store sealed at -20°C; in solution -80°C (up to 6 months) or -20°C (up to 1 month).
- Used to study benzoate metabolism and CoA-dependent pathways in vitro.
Medchemexpress LLC Vecuronium bromide | 50700-72-6 | MFCD00867762 | 99.9% | 100 MG
Vecuronium bromide is a non-depolarizing neuromuscular blocking agent. It also functions as a nicotinic acetylcholine receptor (nAChR) inhibitor and a muscle relaxant. This compound can be used for pre-surgical anesthesia and is intended for research use only.
- Non-depolarizing neuromuscular blocking agent
- Inhibits nicotinic acetylcholine receptors (nAChR)
- Acts as a muscle relaxant
- Can be used for pre-surgical anesthesia
- Suitable for research applications only
Medchemexpress LLC 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone | 4551-69-3 | 99.9% | 278.31 | 1 G
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a heterocyclic compound featuring a five-membered ring structure. It serves as a versatile compound in scientific research.
- Can be used as a starting material for organic synthesis.
- Functions as a reagent for organic transformation.
- Acts as a biological probe for studying biological processes.
- Utilized as a biomaterial or organic compound for life sciences research.
Medchemexpress LLC (2e)-1-(3,4-dimethoxyphenyl)-5-fluoro-3-(4-fluorophenyl)-2-(2-fluorophenyl)pent-1-en-4-one bromide | 1390654-28-0 | >98.8% | 524.38 | 100 MG
KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hindering high-salt-induced NFAT5 and its target gene expressions. KRN2 also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence in the upstream site of Nfat5 exon 1.
- Effectively suppresses AIA in which innate immune cells play a predominant role.
- Effectively suppresses CIA as well as AIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.